o-Phenylenediamine and its salts (CAS no. 95-54-5) 

Definition
o-Phenylenediamine (o-PD), also known as ortho-phenylenediamine, is an organic compound with the formula C6H4(NH2)2. It is one of the isomers of phenylenediamine, characterized by the arrangement of amine groups (-NH2) at the 1 and 2 positions of the benzene ring. Its salts are derived when the amine groups react with acids.

Usage in Cosmetics and Household Products
o-Phenylenediamine and its salts are primarily used as intermediates in the synthesis of dyes, pigments, and other chemicals. In cosmetics, they find usage as ingredients in hair dyes, where they help achieve the desired color. They may also be used in other cosmetic formulations like skin-pigmentation products.

Other Names/Synonyms
  • 1,2-Diaminobenzene
  • 1,2-Phenylenediamine
  • o-Diaminobenzene
Skin Sensitivities and Allergies
o-Phenylenediamine and its salts are known to cause skin sensitization and allergic reactions in some individuals. Contact with the skin can lead to symptoms like redness, itching, and hives. It's particularly concerning for individuals with sensitive skin or those with pre-existing skin conditions. The risk of allergic reactions is often highlighted on the packaging of products containing o-Phenylenediamine, and patch tests are recommended before use.

Other Risks
Apart from skin allergies, o-Phenylenediamine can pose other health risks. Prolonged exposure or large doses can lead to more severe health issues such as respiratory issues or, in extreme cases, organ damage. The toxicity of o-Phenylenediamine and its salts makes them a concern for human health and safety.

Regulatory Ban
As of now, there isn't specific information regarding a ban on o-Phenylenediamine and its salts in the provided California Assembly Bill No. 496. However, due to its potential for causing skin sensitization and other health issues, its usage in cosmetics and personal care products may be restricted or regulated in certain regions. Consumers are advised to exercise caution and follow recommended guidelines when using products containing o-Phenylenediamine or its salts, especially individuals with sensitive skin or known allergies to dye ingredients.

Conclusion
o-Phenylenediamine and its salts are used in the cosmetic industry, mainly in hair dye products, but come with associated risks of skin sensitization and other health concerns. It's crucial for consumers, especially those with sensitive skin, to be aware of these risks and follow recommended safety guidelines, like patch testing, to mitigate potential adverse reactions.

How safe is it?

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