Caine Mix (True Test: Benzocaine,Tetracaine,Dibucaine, aka Caine Mix III; Strict Cross reactors: removes Parabens, PABA)

Caine mix I consists of:

Caine mix II consists of:

Caine mix III consists of:

Caine mix IV consists of:

Caines are used primarily as a topical anesthetic in many kinds of products. 

Patient sensitive to Benzocaine should all avoid all products claiming topical relief of pain or itching unless the product is clearly labeled and Benzocaine and Tetracaine are not included. Such agents can be used if they contain only Dibucaine or Lidocaine.  Persons sensitive to Benzocaine may have a serious reaction to related anesthetic agents derived from Benzoic Acid when given

by injection from dentists, physicians, or other health care workers such individuals should always be advised of the patient’s allergy to Benzocaine. Patients should be able to tolerate other chemically related agents without difficulty, including Lidocaine and Mepivacaine. Benzocaine and Tetracaine-sensitive individuals may also have to avoid PABA and PABA esters containing sunscreens, permanent hair dye (p-Phenylenediamine), certain diuretics or fluid pills (Hydrochlorothiazide), oral antidiabetic medications (sulfonylureas), certain antibiotics including sulfa drugs, PAS, azo and aniline dyes, and an important cardiac medication (Procainamide). Allergic persons should always notify appropriate health care workers.

Patients who are allergic to Caine mix must undergo further testing to determine the component of the mix to which they are allergic. If they are allergic to Benzocaine and Tetracaine, the preceding recommendations apply. If they are allergic to Dibucaine, they must avoid that agent in topical and injectable form and, in addition, should avoid lidocaine, other related amide anesthetics like Mepivacaine, and Quinoline anti-infectives like Iodochlorhydroxyquin.

Other names for contents in Caine Mix IV:

Esters